ProSpec-Eotaxin Human, His,嗜酸性粒细胞趋化素人重组体 CHM-344

  • Eotaxin Human, His

  • Eotaxin Human Recombinant , His Tag
  • CHM-344

Catalogue number

CHM-344

Synonyms

Small inducible cytokine A11, CCL11, Eosinophil chemotactic protein, chemokine ligand 11, SCYA11, MGC22554.

Introduction

趋化因子配体 11 是一种小细胞因子,属于 CC 趋化因子家族,也称为 eotaxin。 CCL11 通过诱导其趋化性选择性地募集嗜酸性粒细胞,因此与过敏反应有关。 CCL11 的作用是通过其与称为趋化因子受体的 G 蛋白连接受体的结合来介导的。 CCL11为其配体的趋化因子受体包括CCR2、CCR3和CCR5。 人类 CCL11 的基因在三个外显子上编码,位于第 17 号染色体上。

Description

Eotaxin His Tag Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 74 amino acids fragment corresponding to the mature Eotaxin protein and having a molecular mass of 8345.9 Dalton with an amino-terminal hexahistidine tag.
The Eotaxin-His is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

Eotaxin-His is supplied liquid In Phosphate Buffered Saline pH7.4 containing 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.

Purity

Greater than 90.0% as determined by -PAGE

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGPASVPTTC CFNLANRKIP LQRLESYRRI TSGKCPQKAV IFKTKLAKDI CADPKKKWVQ DSMKYLDQKS PTPKP

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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