ProSpec-GRO a Rat,GRO-Alpha 大鼠重组 CHM-375

Growth-regulated protein alpha, CXCL1, Melanoma growth stimulatory activity, MGSA, Neutrophil-activating protein 3, NAP-3, GRO-alpha, chemokine ligand 1, GRO1, GROa, SCYB1, MGSA-a, MGSA alpha.

趋化因子配体 1 是一种小细胞因子，属于 CXC 趋化因子家族，以前称为 GRO1 致癌基因、中性粒细胞激活蛋白 3 和黑色素瘤生长刺激活性α。 它由人类黑色素瘤细胞分泌，具有促有丝分裂特性，并与黑色素瘤发病机制有关。 CXCL1由巨噬细胞、中性粒细胞和上皮细胞表达，具有中性粒细胞趋化活性。 CXCL1 通过抑制少突胶质细胞前体的迁移在脊髓发育中发挥作用，并参与血管生成、炎症、伤口愈合和肿瘤发生的过程。 这种趋化因子通过趋化因子受体 CXCR2 发出信号来引发其作用。 CXCL1 基因位于人类第 4 号染色体上，位于其他 CXC 趋化因子基因中。

CXCL1 Rat Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 73 amino acids and having a molecular mass of 7.8 kDa.
The Rat CXCL1 is purified by proprietary chromatographic techniques.

Escherichia Coli.

Sterile Filtered White lyophilized powder.

Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH 7.4, and 150mM NaCl.

It is recommended to reconstitute the lyophilized CXCL1 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

冻干的 CXCL1 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。 重组后，CXCL1 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。
对于长期储存，建议添加载体蛋白。
请防止冻融循环。

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA CLDPEAPMVQ KIVQKMLKGV PK.

Determined by its ability to chemoattract rat neutrophils using a concentration range of 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.