ProSpec-HCC 1 Human His,CHM-253

ProSpec-HCC 1 Human His,CHM-253,它也通常称为HCC-1。 它是作为一种蛋白质前体产生的,经过加工产生一种成熟的活性蛋白质,该蛋白质含有 74 个氨基酸,其氨基酸组成与 CCL3 和 CCL4 有 46% 的相同性。

  • HCC 1 Human, His

  • HCC-1 Human Recombinant, His Tag
  • CHM-253

Catalogue number

CHM-253

Synonyms

Small inducible cytokine A14, CCL14, Chemokine CC-1/CC-3, HCC-1/HCC-3, HCC-1, NCC-2, chemokine ligand 14, CC-1, CC-3, CKb1, MCIF, SY14, HCC-1, HCC-3, SCYL2, SCYA14.

Introduction

Chemokine ligand 14 is a small cytokine belonging to the CC chemokine family. It is also commonly known as HCC-1. It is produced as a protein precursor that is procesed to generate a mature active protein containing 74 amino acids that and is 46% identical in amino acid composition to CCL3 and CCL4. This chemokine is expressed in various tissues including spleen, bone marrow, liver, muscle, and gut. CCL13 activates monocytes, but does not induce their chemotaxis. Human CCL13 is located on chromosome 17 within a cluster of other chemokines belonging to the CC family.

趋化因子配体 14 是一种属于 CC 趋化因子家族的小细胞因子。 它也通常称为HCC-1。 它是作为一种蛋白质前体产生的,经过加工产生一种成熟的活性蛋白质,该蛋白质含有 74 个氨基酸,其氨基酸组成与 CCL3 和 CCL4 有 46% 的相同性。 这种趋化因子在各种组织中表达,包括脾脏、骨髓、肝脏、肌肉和肠道。 CCL13 激活单核细胞,但不诱导其趋化性。 人类 CCL13 位于属于 CC 家族的其他趋化因子簇内的 17 号染色体上。

Description

HCC-1 Human Recombinant fused with a 21 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 95 amino acids and having a molecular mass of 10.9kDa. The HCC-1 is purified by proprietary chromatographic techniques.
HCC-1 Human Recombinant 在 N 末端融合了 21 个氨基酸的 His 标签,在大肠杆菌中产生,是一条含有 95 个氨基酸且分子量为 10.9kDa 的单一非糖基化多肽链。 HCC-1 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

The HCC-1 solution contains Phosphate Buffered Saline pH7.4 containing 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

如果整个小瓶将在 2-4 周内使用,请在 4°C 下储存。 储存,在 -20°C 下冷冻更长时间。
对于长期储存,建议添加载体蛋白。
避免多次冻融循环。

Purity

Greater than 95.0% as determined by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MTKTESSSRG PYHPSECCFT YTTYKIPRQR IMDYYETNSQ CSKPGIVFIT KRGHSVCTNP SDKWVQDYIK DMKEN.

Usage

ProSpec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。

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