Catalogue number
CHM-254
Synonyms
Small inducible cytokine A1, CCL1, T lymphocyte-secreted protein I-309, chemokine ligand 1, P500, SISe, TCA3, I-309, SCYA1.
Introduction
Chemokine ligand 1 is a small glycoprotein secreted by activated T cells that belongs to a family inflammatory cytokines known as chemokines. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with a cell surface chemokine receptor called CCR8. This chemokine resides in a large cluster of CC chemokines on human chromosome 17.
趋化因子配体 1 是一种由活化的 T 细胞分泌的小糖蛋白,属于称为趋化因子的炎性细胞因子家族。 CCL1 通过与称为 CCR8 的细胞表面趋化因子受体相互作用来吸引单核细胞、NK 细胞、未成熟 B 细胞和树突状细胞。 这种趋化因子存在于人类 17 号染色体上的一大群 CC 趋化因子中。
Description
I-309 Human Recombinant fused with a 21 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 94 amino acids and having a molecular mass of 10.8kDa. The I-309 is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
The I-309 solution contains 20mM Tris-HCl buffer , 2mM DTT, 10% glycerol and 50mM NaCl.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by -PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MKSMQVPFSR CCFSFAEQEI PLRAILCYRN TSSICSNEGL IFKLKRGKEA CALDTVGWVQ RHRKMLRHCP SKRK.
Usage
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Related Products
-
I 309 Human