ProSpec,Lymphotactin Human,Lymhotactin 人重组CHM-314

XCL1, Cytokine SCM-1, ATAC, Lymphotaxin, SCM-1-alpha, Small inducible cytokine C1, XC chemokine ligand 1, LTN, LPTN, SCM1, SCM-1, SCYC1, SCM-1a.

Chemokine ligand is a small cytokine belonging to the XC chemokine family that is also known as lymphotactin. It is found in high levels in spleen, thymus, intestine and peripheral blood leukocytes, and at lower levels in lung, prostate gland and ovary. Cellular sources for XCL1 include activated thymic and peripheral blood CD8+ T cells. This chemokine attracts T cells. In humans, XCL1 is closely related to another chemokine called XCL2, whose geneis found at the same locus on chromosome 1. XCL1 induces it chemotactic function by binding to a chemokine receptor called XCR1.

趋化因子配体是一种属于 XC 趋化因子家族的小细胞因子，也称为淋巴趋化素。 它在脾脏、胸腺、肠和外周血白细胞中含量较高，在肺、前列腺和卵巢中含量较低。 XCL1 的细胞来源包括活化的胸腺和外周血 CD8+ T 细胞。 这种趋化因子会吸引 T 细胞。 在人类中，XCL1 与另一种称为 XCL2 的趋化因子密切相关，后者的基因位于 1 号染色体的同一位点。XCL1 通过与称为 XCR1 的趋化因子受体结合来诱导其趋化功能。

Lymphotactin Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 92 amino acids and having a molecular mass of 10007 Dalton.
The Lymphotactin is purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 Lymphotactin Human Recombinant 是一种单一的、非糖基化的多肽链，含有 92 个氨基酸，分子量为 10007 道尔顿。
Lymphotactin 通过专有的色谱技术进行纯化。

Escherichia Coli.

Sterile Filtered White lyophilized powder.

The XCL1 was lyophilized from a concentrated solution in water containing no additives.

It is recommended to reconstitute the lyophilized Lymphotactin in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Lyophilized Lymphotactin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution XCL1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please avoid freeze-thaw cycles.

Greater than 99.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

The sequence of the first five N-terminal amino acids was determined and was found to be Gln-Ser-Glu-Val-Ser.

The Biological activity is calculated by its ability to chemoattract human T cells at 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.