ProSpec,MCP 3 Human,单核细胞趋化蛋白3人重组体CHM-317

Small inducible cytokine A7, CCL7, Monocyte chemotactic protein 3, MCP-3, Monocyte chemoattractant protein 3, NC28, chemokine ligand 7, FIC, MARC, MCP3, SCYA6, SCYA7, MGC138463, MGC138465.

Chemokine ligand 7 is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 . Due to CCL7 possessing two adjacent N-terminal cysteine residues in its mature protein, it is classified among the subfamily of chemokines known as CC chemokines. CCL7 specifically attracts monocytes, and regulates macrophage function. It is produced by certain tumor cell lines and by macrophages. This chemokine is located on chromosome 17 in humans, in a large cluster containing many other CC chemokines and is most closely related to CCL2.

趋化因子配体 7 是一种称为趋化因子的小细胞因子，以前称为单核细胞特异性趋化因子 3。 由于 CCL7 在其成熟蛋白中具有两个相邻的 N 末端半胱氨酸残基，因此它被归类为称为 CC 趋化因子的趋化因子亚家族。 CCL7 特异性吸引单核细胞，并调节巨噬细胞功能。 它由某些肿瘤细胞系和巨噬细胞产生。 这种趋化因子位于人类的第 17 号染色体上，位于一个包含许多其他 CC 趋化因子的大簇中，并且与 CCL2 关系最密切。

Monocyte Chemotactic Protein-3 Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 76 amino acids and having a molecular mass of 9011 Dalton.
The MCP-3 is purified by proprietary chromatographic techniques.

在大肠杆菌中产生的单核细胞趋化蛋白 3 人重组体是一种非糖基化的多肽链，含有 76 个氨基酸，分子量为 9011 道尔顿。
MCP-3 通过专有的色谱技术进行纯化。

Escherichia Coli.

Sterile Filtered White lyophilized powder.

The protein was lyophilized from a concentrated sterile solution containing no additives.

It is recommended to reconstitute the lyophilized Monocyte Chemotactic Protein-3in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Lyophilized MCP-3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL7 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

冻干的 MCP-3 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。 复溶后，CCL7 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。 对于长期储存，建议添加载体蛋白。
请防止冻融循环。

Greater than 98.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

The sequence of the first five N-terminal amino acids was determined and was found to be Gln-Pro-Val-Gly-Ile.

The specific activity as determined by the ability of MCP-3 to chemoattract human peripheral blood at 8 – 80ng/ml corresponding to a Specific Activity of 12,500-125,000IU/mg.

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.