ProSpec CHM-275,MCP 4 Human His,CHM-275

ProSpec CHM-275,MCP 4 Human His,CHM-275,CCL13 蛋白通过结合细胞表面 G 蛋白连接的趋化因子受体（如 CCR2、CCR3 和 CCR5）在单核细胞、嗜酸性粒细胞、T 淋巴细胞和嗜碱性粒细胞中诱导趋化性。 CCL13 由炎性细胞因子 IL1 和 TNFA 诱导。

  • MCP 4 Human, His

  • Monocyte Chemotactic Protein-4 Human Recombinant , His-Tag
  • CHM-275

Catalogue number

CHM-275

Synonyms

CKb10, MCP-4, NCC-1, NCC1, SCYA1, SCYL1, CK-beta-10, Small-inducible cytokine A13.

Introduction

CCL13 chemokine is part of the CC chemokine family . CCL13 protein induces chemotaxis in monocytes, eosinophils, T lymphocytes, and basophils by binding cell surface G-protein linked chemokine receptors such as CCR2, CCR3 and CCR5. CCL13 is induced by the inflammatory cytokines IL1 & TNFA.
CCL13趋化因子是CC趋化因子家族的一部分。 CCL13 蛋白通过结合细胞表面 G 蛋白连接的趋化因子受体（如 CCR2、CCR3 和 CCR5）在单核细胞、嗜酸性粒细胞、T 淋巴细胞和嗜碱性粒细胞中诱导趋化性。 CCL13 由炎性细胞因子 IL1 和 TNFA 诱导。

Description

MCP4 Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 96 amino acids and having a molecular mass of 10.8 kDa.
The MCP-4 is fused to 21 amino acids His-Tag at N-terminus and purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered colorless clear solution.

Formulation

The His Tag 0.25mg/ml MCP4 protein solution contains PBS pH-7.4, 1mM DTT, 0.1M NaCl and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
Please avoid freeze thaw cycles.

Purity

Greater than 90.0% as determined by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MQPDALNVPS TCCFTFSSKK ISLQRLKSYV ITTSRCPQKA VIFRTKLGKE ICADPKEKWV QNYMKHLGRK
.AHTLKT

Usage

Prospecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.