ProSpec,MCP1 Rat Sf9 CHM-044,单核细胞趋化蛋白 1 大鼠重组体Sf9

Small inducible cytokine A2, CCL2, Monocyte chemotactic protein 1, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, MCAF, Monocyte secretory protein JE, HC11, chemokine ligand 2, MCP1, SCYA2, GDCF-2, SMC-CF, HSMCR30, MGC9434, GDCF-2 HC11

Chemokine ligand 2 is a small cytokine belongs to the CC chemokine family which is also known as monocyte chemotactic protein-1 . MCP 1 is found at the site of tooth eruption and bone degradation. In the bone, CCL2 is expressed by mature osteoclasts. CCL2 recruits immune cells, such as monocytes, to sites of tissue injury and infection. MCP 1is produced as a protein precursor containing signal peptide of 23 amino acids and a mature peptide of 76 amino acids. As with many other CC chemokines, CCL2 is located on chromosome 17 in humans. The cell surface receptors that bind CCL2 are CCR2 and CCR5.

趋化因子配体 2 是一种小细胞因子，属于 CC 趋化因子家族，也称为单核细胞趋化蛋白 1。 MCP 1 存在于牙齿萌出和骨骼退化的部位。 在骨骼中，CCL2 由成熟的破骨细胞表达。 CCL2 将免疫细胞（例如单核细胞）募集到组织损伤和感染部位。 MCP 1 作为蛋白质前体产生，含有 23 个氨基酸的信号肽和 76 个氨基酸的成熟肽。 与许多其他 CC 趋化因子一样，CCL2 位于人类的第 17 号染色体上。 结合 CCL2 的细胞表面受体是 CCR2 和 CCR5。

MCP1 Rat Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 134 amino acids and having a molecular mass of 15.1kDa.
MCP1 is fused to a 6 amino acid His tag at C-terminus and purified by proprietary chromatographic techniques.

在 Sf9 杆状病毒细胞中产生的 MCP1 大鼠重组体是单条糖基化多肽链，含有 134 个氨基酸，分子量为 15.1kDa。
MCP1 在 C 末端与 6 个氨基酸的 His 标签融合，并通过专有色谱技术进行纯化。

Sf9, Baculovirus cells

Sterile filtered colorless solution.

The MCP1 Rat protein solution contains 10% glycerol and Phosphate-Buffered Saline .

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Greater than 90% as determined by -PAGE.

ADPQPDAVNA PLTCCYSFTG KMIPMSRLEN YKRITSSRCP KEAVVFVTKL KREICADPNK EWVQKYIRKL DQNQVRSETT VFYKIASTLR TSAPLNVNLT HKSEANASTL FSTTTSSTSV EVTSMTENHH HHHH

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