ProSpec,MIG Human CHM-333,MIG 人重组CHM-333

Small inducible cytokine B9, CXCL9, Gamma INF-induced monokine, MIG, chemokine ligand 9, CMK, Humig, SCYB9, crg-10, monokine induced by gamma-INF.

Chemokine ligand 9 is a small cytokine belonging to the CXC chemokine family that is also known as Monokine induced by gamma INF . CXCL9 is a T-cell chemoattractant, which is induced by IFN-?. It is closely related to two other CXC chemokines called CXCL10 and CXCL11, whose genes are located near the gene for CXCL9 on human chromosome 4. CXCL9, CXCL10 and CXCL11 all elicit their chemotactic functions by interacting with the chemokine receptor CXCR3.

趋化因子配体 9 是一种小细胞因子，属于 CXC 趋化因子家族，也称为由 γ INF 诱导的 Monokine。 CXCL9 是一种 T 细胞趋化剂，由 IFN-α 诱导。 它与另外两种称为 CXCL10 和 CXCL11 的 CXC 趋化因子密切相关，它们的基因位于人类 4 号染色体上的 CXCL9 基因附近。CXCL9、CXCL10 和 CXCL11 都通过与趋化因子受体 CXCR3 相互作用而引发其趋化功能。

MIG Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 103 amino acids and having a molecular mass of 11700 Dalton. The MIG is purified by proprietary chromatographic techniques.

Escherichia Coli.

Sterile Filtered White lyophilized powder.

Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH 7.4, 50mM NaCl.

It is recommended to reconstitute the lyophilized MIG in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

建议在不低于 100µg/ml 的无菌 18MΩ-cm H2O 中复溶冻干 MIG，然后可以进一步稀释成其他水溶液。

Lyophilized MIG although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL9 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

TPVVRKGRCSCISTNQGTIHLQSLKDLKQFAPSPSCEKIEIIATLKNGVQTCLNPDS
ADVKELIKKWEKQVSQKKKQKNGKKHQKKKVLKVRKSQRSRQKKTT.

Determined by its ability to chemoattract human peripheral blood T-Lymphocytes using a concentration range of 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.