- Description
Catalogue number
CYT-1038
Synonyms
Epithelial mitogen, EPG, Epithelial Mitogen Homolog , Epithelial Mitogen Homolog, ALGV3072, PRO9904, Epigen, EPGN.
Introduction
EPGN is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. EPGN is produced in numerous tissues, including the testis, liver, heart and in certain tumor cells. EPGN is mitogenic for fibroblasts and epithelial cells. Human EPGN is originally synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence.
Description
EPGN produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 97 amino acids and having a molecular mass of 10.8kDa .
EPGN is expressed with an 9 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Source
Sf9, Insect cells.
Physical Appearance
Sterile filtered colorless solution.
Formulation
EPGN protein solution contains Phosphate Buffered Saline and 10% glycerol
Stability
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by -PAGE.
Amino acid sequence
ADPAAVTVTP PITAQQGNWT VNKTEADNIE GPIALKFSHL CLEDHNSYCI NGACAFHHEL EKAICRCFTG YTGERCEHLT LTSYAVDSYE KHHHHHH.
Usage
Related Products
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EPGN Human, His
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EPGN Human