ProSpec-Acrp30 Human, Sf9-CYT-1002

Adiponectin, C1Q And Collagen Domain Containing, Adipose Most Abundant Gene Transcript 1 Protein, Adipocyte Complement-Related 30 KDa Protein, 30 KDa Adipocyte Complement-Related Protein, ACRP30, APM-1, GBP28, ACDC, APM1, Adipocyte, C1q And Collagen Domain-Containing Protein, Adipocyte, C1Q And Collagen Domain Containing, Adipose Most Abundant Gene Transcript 1, Adipose Specific Collagen-Like Factor, Gelatin-Binding Protein 28, Gelatin-Binding Protein, Adiponectin Precursor, Adiponectin, ADIPQTL1, ADPN, 30 kDa adipocyte complement-related protein, dipocyte complement-related 30 kDa protein, ACRP30, Adipocyte, C1q and collagen domain-containing protein, Adipose most abundant gene transcript 1 protein, apM-1, Gelatin-binding protein.

含有脂联素、C1Q 和胶原蛋白结构域、脂肪最丰富的基因转录 1 蛋白、脂肪细胞补体相关 30 KDa 蛋白、30 KDa 脂肪细胞补体相关蛋白、ACRP30、APM-1、GBP28、ACDC、APM1、脂肪细胞、C1q 和胶原蛋白结构域 -含有蛋白质、脂肪细胞、C1Q 和胶原蛋白结构域、脂肪最丰富的基因转录物 1、脂肪特异性胶原蛋白样因子、明胶结合蛋白 28、明胶结合蛋白、脂联素前体、脂联素、ADIPQTL1、ADPN、30 kDa 脂肪细胞补体 相关蛋白、双细胞补体相关 30 kDa 蛋白、ACRP30、脂肪细胞、C1q 和含有胶原结构域的蛋白、脂肪最丰富的基因转录物 1 蛋白、apM-1、明胶结合蛋白。

The adipose tissue exclusively expresses and secretes Adiponectin . Acrp30 is involved in various physiological processes such as energy homeostasis, insulin sensitivity, hormonal processes, fatty acid metabolism and obesity.
Adiponectin circulates in the plasma. Decreased levels of Adiponectin are associated with insulin resistance and hyperinsulinemia, as seen in people with obesity insulin resistance, and diabetes type 2, whose plasma levels of adiponectin are reduced.
The modular structure of Acrp30 is comprised of N-terminal collagenous domain followed by a C-terminal globular domain.
Acrp30 also acts as a significant negative regulator in hematopoiesis and immune systems; it may be involved in ending inflammatory responses through its inhibitory functions. Adiponectin inhibits endothelial NF-kappa-b signaling through a cAMP-dependent pathway, it also inhibits TNF-alpha- induced expression of endothelial adhesion molecules.

脂肪组织专门表达和分泌脂联素。 Acrp30 参与多种生理过程，例如能量稳态、胰岛素敏感性、激素过程、脂肪酸代谢和肥胖。
脂联素在血浆中循环。 脂联素水平降低与胰岛素抵抗和高胰岛素血症有关，如肥胖胰岛素抵抗和 2 型糖尿病患者的血浆脂联素水平降低。
Acrp30 的模块化结构由 N 端胶原结构域和 C 端球状结构域组成。
Acrp30 还在造血和免疫系统中充当重要的负调节剂； 它可能通过其抑制功能参与结束炎症反应。 脂联素通过 cAMP 依赖性途径抑制内皮 NF-kappa-b 信号传导，它还抑制 TNF-α 诱导的内皮粘附分子的表达。

Acrp30 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 146 amino acids and having a molecular mass of 16.9kDa. . Acrp30 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

在 Sf9 杆状病毒细胞中产生的 Acrp30 Human Recombinant 是单条糖基化多肽链，包含 146 个氨基酸，分子量为 16.9kDa。 . Acrp30 在 C 末端用 6 个氨基酸 His 标签表达，并通过专有色谱技术进行纯化。

Sf9, Baculovirus cells.

Sterile Filtered clear solution.

Acrp30 protein solution contains Phosphate Buffered Saline and 10% glycerol.

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。 储存，在 -20°C 下冷冻更长时间。
对于长期储存，建议添加载体蛋白。
避免多次冻融循环。

Greater than 95.0% as determined by -PAGE.

ADPEGAYVYR SAFSVGLETY VTIPNMPIRF TKIFYNQQNH YDGSTGKFHC NIPGLYYFAY HITVYMKDVK VSLFKKDKAM LFTYDQYQEN NVDQASGSVL LHLEVGDQVW LQVYGEGERN GLYADNDNDS TFTGFLLYHD HHHHHH.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。