ProSpec-GDF5 Mouse, His/CYT-852,Growth differentiation factor 5 Mouse Recombinant, His Tag

GDF5 Mouse, His

Growth differentiation factor 5 Mouse Recombinant, His Tag
CYT-852
5µg
20µg
1mg

Catalogue number

CYT-852

Synonyms

Bmp-14, Bp, GDF-5, Bone morphogenetic protein 14, GDF5.

Introduction

GDF-5 is a member of the bone morphogenetic protein family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.

GDF-5 是骨形态发生蛋白家族和 TGF-β 超家族的成员。这组蛋白质的特征在于多元蛋白水解加工位点，该位点被切割以产生含有七个保守半胱氨酸残基的成熟蛋白。该家族的成员是胚胎和成人组织中细胞生长和分化的调节剂。该基因的突变与Hunter-Thompson型肢端发育不良有关；短指，C型；和软骨发育不良，Grebe型。这些关联证实基因产物在骨骼发育中发挥作用。

Description

GDF5 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 143 amino acids and having a molecular mass of 16kDa.
GDF5 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 GDF5 Mouse Recombinant 是一条单一的、非糖基化的多肽链，包含 143 个氨基酸，分子量为 16kDa。
GDF5 在 N 端与 23 个氨基酸的 His-tag 融合，并通过专有色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

GDF5 protein solution containing 20mM Tris-HCl buffer and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。储存，在 -20°C 下冷冻更长时间。
对于长期储存，建议添加载体蛋白。
避免多次冻融循环。

Purity

Greater than 90.0% as determined by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSAPLANRQ GKRPSKNLKA RCSRKALHVN FKDMGWDDWI IAPLEYEAFH CEGLCEFPLR SHLEPTNHAV IQTLMNSMDP ESTPPTCCVP TRLSPISILF IDSANNVVYK QYEDMVVESC GCR.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.