BST1 Human
Bone Marrow Stromal Cell Antigen 1 Human Recombinant
CYT-1071
ProSpec-BST1 Human/CYT-1071 2µg
ProSpec-BST1 Human/CYT-1071 10µg
ProSpec-BST1 Human/CYT-1071 1mg
Catalogue number
CYT-1071
Synonyms
Bone Marrow Stromal Cell Antigen 1, ADP-Ribosyl Cyclase 2, Bone Marrow Stromal Antigen 1, Cyclic ADP-Ribose Hydrolase 2, NAD Nucleosidase, CADPr Hydrolase 2, ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 2, CD157 Antigen, EC 3.2.2.6, CD157, BST-1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2, ADP-ribosyl cyclase 2, Bone marrow stromal antigen 1, Cyclic ADP-ribose hydrolase 2, cADPr hydrolase 2.
骨髓基质细胞抗原 1、ADP-核糖基环化酶 2、骨髓基质抗原 1、环状 ADP-核糖水解酶 2、NAD 核苷酶、CADPr 水解酶 2、ADP-核糖基环化酶/环状 ADP-核糖水解酶 2、CD157 抗原、EC 3.2 .2.6、CD157、BST-1、ADP-核糖基环化酶/环状 ADP-核糖水解酶 2、ADP-核糖基环化酶 2、骨髓基质抗原 1、环状 ADP-核糖水解酶 2、cADPr 水解酶 2。
Introduction
BST1 , is a GPI anchored membrane protein which is part of the CD38 family. BST1 was initially recognized as a bone marrow stromal cell molecule. BST1 is an ectoenzyme sharing more than a few features with ADP-ribosyl cyclase CD38. BST1 together with CD38, exhibit both DP-ribosyl cyclase and cyclinc ADP ribose hydrolase activities. BST1 participates in rheumatoid arthritis due to its enhanced expression in RA-derived bone marrow stromal cell lines. Moreover, BST1 is expressed by cells of the myeloid lineage and could perform as a receptor with a signal transduction capability.
BST1 是一种 GPI 锚定膜蛋白,它是 CD38 家族的一部分。 BST1 最初被认为是一种骨髓基质细胞分子。 BST1 是一种与 ADP-核糖基环化酶 CD38 共享多个特征的外酶。 BST1 与 CD38 一起表现出 DP-核糖基环化酶和 cyclinc ADP 核糖水解酶活性。 BST1 参与类风湿性关节炎,因为它在 RA 衍生的骨髓基质细胞系中表达增强。 此外,BST1 由髓系细胞表达,可以作为具有信号转导能力的受体发挥作用。
Description
BST1 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 267 amino acids and having a molecular mass of 30.5kDa. .
BST1 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
在 Sf9 杆状病毒细胞中产生的 BST1 是单条糖基化多肽链,包含 267 个氨基酸,分子量为 30.5kDa。 .
BST1 在 C 末端用 6 个氨基酸的 His 标签表达,并通过专有色谱技术进行纯化。
Source
Sf9, Baculovirus cells.
Physical Appearance
Sterile filtered colorless solution.
Formulation
BST1 protein solution contains 10% glycerol & Phosphate Buffered Saline .
Stability
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
对于长期储存,建议添加载体蛋白。
避免多次冻融循环。
Purity
Greater than 95.0% as determined by -PAGE.
Amino acid sequence
RWRGEGTSAH LRDIFLGRCA EYRALLSPEQ RNKNCTAIWE AFKVALDKDP CSVLPSDYDL FINLSRHSIP RDKSLFWENS HLLVNSFADN TRRFMPLSDV LYGRVADFLS WCRQKNDSGL DYQSCPTSED CENNPVDSFW KRASIQYSKD SSGVIHVMLN GSEPTGAYPI KGFFADYEIP NLQKEKITRI EIWVMHEIGG PNVESCGEGS MKVLEKRLKD MGFQYSCIND YRPVKLLQCV DHSTHPDCAL KSAAAATQRK AHHHHHH.