ProSpec-FAS Human, Sf9/CYT-1153 | Lumiprobe官网中国授权代理商

FAS Human, Sf9

sFas Receptor Human Recombinant, Sf9
CYT-1153
2µg
10µg
1mg

Catalogue number

CYT-1153

Synonyms

Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, CD95, FAS, APT1, FAS1, APO-1, FASTM, ALPS1A, TNFRSF6.

Introduction

FAS or tumor necrosis factor receptor superfamily member 6 or TNFRSF6, is part of the death receptor family, which is part of the TNF receptor protein family. TNFRSF6 has a crucial part in regulating viral infections. FAS protein can be found in almost all cell types, when its cognate ligand can be found in activated T cells, NK cells & dendritic cells. The regulating protein of FasL & TRAIL on HCMV-infected dendritic enhances direct destruction of activated T lymphocytes. furthermore, subvertneutrophil function in HCMV retinitis can occur when FasL is activated in HCMV infected retinal pigment epithelial cells.

FAS或肿瘤坏死因子受体超家族成员6或TNFRSF6，是死亡受体家族的一部分，它是TNF受体蛋白家族的一部分。 TNFRSF6 在调节病毒感染中起着至关重要的作用。 FAS 蛋白几乎可以在所有细胞类型中找到，而它的同源配体可以在活化的 T 细胞、NK 细胞和树突状细胞中找到。 HCMV 感染树突上的 FasL 和 TRAIL 调节蛋白增强了活化 T 淋巴细胞的直接破坏。此外，当在 HCMV 感染的视网膜色素上皮细胞中激活 FasL 时，可能会发生 HCMV 视网膜炎中的亚中性粒细胞功能。

Description

FAS Human Recombinant produced in Baculovirus is a single glycosylated polypeptide chain containing 156 amino acids and having a molecular mass of 17.7KDa.
FAS is fused to a 8 amino acid His-Tag at C-terminus and purified by proprietary chromatographic techniques.

在杆状病毒中产生的 FAS Human Recombinant 是单条糖基化多肽链，包含 156 个氨基酸，分子量为 17.7KDa。
FAS 在 C 端与 8 个氨基酸的 His-Tag 融合，并通过专有色谱技术进行纯化。

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

FAS protein contains 10% glycerol and Phosphate-Buffered Saline .

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。储存，在 -20°C 下冷冻更长时间。
对于长期储存，建议添加载体蛋白。
避免多次冻融循环。

Purity

Greater than 95.0% as determined by -PAGE.

Amino acid sequence

QVTDINSKGL ELRKTVTTVE TQNLEGLHHD GQFCHKPCPP GERKARDCTV NGDEPDCVPC QEGKEYTDKA HFSSKCRRCR LCDEGHGLEV EINCTRTQNT KCRCKPNFFC NSTVCEHCDP CTKCEHGIIK ECTLTSNTKC KEEGSRSNLE HHHHHH

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.