ProSpec-FST Human, Sf9/CYT-865

Follistatin, FS, Activin-Binding Protein, Follistatin Isoform FST317, FST.

Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. Follistatin binds directly to activin and functions as an activin antagonist. specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone .

卵泡抑素是一种单链性腺蛋白，可特异性抑制促卵泡激素的释放。 单个 FST 基因编码两种同种型，FST317 和 FST344，分别含有 317 和 344 个氨基酸，由前体 mRNA 的可变剪接产生。 在一项研究中，测试了 37 个候选基因与 150 个家庭的多囊卵巢综合征或高雄激素血症的关联和关联，发现了 PCOS 和卵泡抑素之间关联的证据。 卵泡抑素直接与激活素结合并作为激活素拮抗剂发挥作用。 垂体促卵泡激素的生物合成和分泌的特异性抑制剂。

Sf9, Baculovirus cells.

Sterile filtered colorless solution.

FST protein solution contains Phosphate buffered saline and 10% glycerol.

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Greater than 90.0% as determined by -PAGE.

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ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.