ProSpec-IFN b 1a Human/CYT-236

Leukocyte IFN, B cell IFN, Type I IFN, IFNB1, IFB, IFF, IFNB, IFN-b 1a ,MGC96956.

IFN-beta has antiviral, antibacterial and anticancer activities.

IFN-beta 1a Human Recombinant produced in CHO cells is a single, glycosylated polypeptide chain containing 166 amino acids and having a molecular mass of 22500 Dalton.
IFN-beta1a is purified by proprietary chromatographic techniques.

在 CHO 细胞中产生的 IFN-beta 1a Human Recombinant 是一条单一的糖基化多肽链，包含 166 个氨基酸，分子量为 22500 道尔顿。
IFN-beta1a 是通过专有的色谱技术纯化的。

CHO cells.

Lyophilized from a solution containing 91 mg Human Albumin, and 620 mg mannitol and 50mM Acetate acid pH 3.8.

It is recommended to reconstitute the lyophilized IFN beta 1a in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

建议在不低于 100µg/ml 的无菌 18MΩ-cm H2O 中重新配制冻干的 IFN beta 1a，然后可以进一步稀释成其他水溶液。

Lyophilized IFN-beta 1a although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFN-Beta1a should be stored at 4°C between 2-7 days and for future use below -18°C.
Please prevent freeze-thaw cycles.

冻干的 IFN-beta 1a 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。 重组后的 IFN-Beta1a 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。
请防止冻融循环。

Greater than 99.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

The specific activity as determined in a viral resistance assay was found to be 270 x 10⁶ IU/mg.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Title:IFNG induces apoptosis in human SH-SY5Y neuroblastoma cells through activation of JAK–STAT signaling and down-regulation of PI3K/Akt pathway.
Publication:Article first published online: 11 NOV 2010 DOI:10.1111/j.1471-4159.2010.07046.x
Link:http://onlinelibrary.wiley.com/doi/10.1111/j.1471-4159.2010.07046.x/full