SAA4 Human
Serum Amyloid A4 Human Recombinant
CYT-002
2µg
10µg
1mg
Catalogue number
CYT-002
Synonyms
Serum amyloid A-4 protein, Constitutively expressed serum amyloid A protein, C-SAA, SAA4, CSAA.
Introduction
SAA4 is a constitutively expressed protein which is a member of the SAA family. SAA4 is a major acute phase reactant and an apolipoprotein of the HDL complex. SAA4 is constitutively expressed only in humans and mice; it is connected almost completely with lipoproteins of the high density range. The physiological function of SAA4 is unknown, and its serum concentration has no association with those of other major apolipoproteins. SAA4 mRNA and protein occurrence in macrophage derived foam cells of coronary and carotid arteries implied a specific role of human SAA4 during inflammation including atherosclerosis.
SAA4是组成型表达的蛋白质,是SAA家族的成员。 SAA4 是主要的急性期反应物和 HDL 复合物的载脂蛋白。 SAA4 仅在人和小鼠中组成型表达; 它几乎完全与高密度范围的脂蛋白相连。 SAA4 的生理功能未知,其血清浓度与其他主要载脂蛋白的浓度无关。 SAA4 mRNA 和蛋白质在冠状动脉和颈动脉巨噬细胞衍生的泡沫细胞中的出现暗示了人类 SAA4 在炎症(包括动脉粥样硬化)过程中的特定作用。
Description
SAA4 Human Recombinant fused with a 21 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 131 amino acids and having a molecular mass of 14.9kDa. The SAA4 is purified by proprietary chromatographic techniques.
SAA4 Human Recombinant 在 N 末端融合了 21 个氨基酸的 His 标签,在大肠杆菌中产生,是一条含有 131 个氨基酸且分子量为 14.9kDa 的单一非糖基化多肽链。 SAA4 通过专有的色谱技术进行纯化。
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
The SAA4 solution contains 20mM Tris-HCl buffer , 20% glycerol, 5mM DTT, 0.2M NaCl and 0.5mM EDTA.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
如果整个小瓶将在 2-4 周内使用,请在 4°C 下储存。 储存,在 -20°C 下冷冻更长时间。
对于长期储存,建议添加载体蛋白。
避免多次冻融循环。
对于长期储存,建议添加载体蛋白。
避免多次冻融循环。
Purity
Greater than 90.0% as determined by -PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MWRSFFKEAL QGVGDMGRAY WDIMISNHQN SNRYLYARGN YDAAQRGPGG VWAAKLISRS RVYLQGLIDY YLFGNSSTVL EDSKSNEKAE EWGRSGKDPD RFRPDGLPKK Y.
Usage
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ProSpec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。