ProSpec-TPO Human, HEK/CYT-115,Thrombopoietin Human Recombinant, HEK

ProSpec-TPO Human, HEK/CYT-115,Thrombopoietin Human Recombinant, HEK,ProSpec代理,ProSpec产品,ProSpec产品目录,ProSpec Cytokines,冻干的血小板生成素虽然在室温下可稳定保存 3 周,但应在 -18°C 以下干燥储存。 复溶后,TPO 应在 4°C 下储存 2-7 天,以备将来在 -18°C 以下使用。

TPO Human, HEK
Thrombopoietin Human Recombinant, HEK
CYT-115
2µg
10µg
1mg

Catalogue number

CYT-115

Synonyms

Megakaryocyte colony-stimulating factor, Myeloproliferative leukemia virus oncogene ligand, C-mpl ligand, ML, Megakaryocyte growth and development factor, MGDF, TPO, MKCSF, MPLLG, MGC163194, THPO.
巨核细胞集落刺激因子、骨髓增殖性白血病病毒癌基因配体、C-mpl配体、ML、巨核细胞生长发育因子、MGDF、TPO、MKCSF、MPLLG、MGC163194、THPO。

Introduction

Thrombopoietin is a glycoprotein hormone produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. It stimulates the production and differentiation of megakaryocytes, the bone marrow cells that fragment into large numbers of platelets.
血小板生成素是一种糖蛋白激素,主要由肝脏和肾脏产生,可调节骨髓的血小板生成。 它刺激巨核细胞的产生和分化,巨核细胞是分裂成大量血小板的骨髓细胞。

Description

Thrombopoietin Human Recombinant produced in HEK cells is a glycosylated monomer, having a molecular weight range of 80-85kDa due to glycosylation.
The TPO is purified by proprietary chromatographic techniques.
HEK 细胞中产生的血小板生成素人重组体是一种糖基化单体,由于糖基化,其分子量范围为 80-85kDa。
TPO 通过专有的色谱技术进行纯化。

Source

HEK.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

The TPO protein was filtered and lyophilized from 0.74mg/ml in 1xPBS.

Solubility

It is recommended to reconstitute the lyophilized Thrombopoietin in sterile PBS containing 0.1% endotoxin-free recombinant HSA.

Stability

Lyophilized Thrombopoietin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution TPO should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.
冻干的血小板生成素虽然在室温下可稳定保存 3 周,但应在 -18°C 以下干燥储存。 复溶后,TPO 应在 4°C 下储存 2-7 天,以备将来在 -18°C 以下使用。
对于长期储存,建议添加载体蛋白。
请防止冻融循环。

Purity

Greater than 95% as obsereved by -PAGE.

Biological Activity

The activity was determined by the dose-dependent stimulation of the proliferation of MO7e cells, the ED50 is 1.15ng/ml.

Amino acid sequence

SPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLG EWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQV RLLLGALQSLLGTQLPPQGRTTAHKDPNAIFLSFQHLLRGKVRFLMLVGG STLCVRRAPPTTAVPSRTSLVLTLNELPNRTSGLLETNFTASARTTGSGLLK WQQGFRAKIPGLLNQTSRSLDQIPGYLNRIHELLNGTRGLFPGPSRRTLGAP DISSGTSDTGSLPPNLQPGYSPSPTHPPTGQYTLFPLPPTLPTPVVQLHPLLPDPSAPTPT

PTSPLLNTSYTHSQNLSQEG

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。

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