TACI Human, Sf9
Tumor Necrosis Factor Receptor 13B Human Recombinant, Sf9
CYT-982
2µg
10µg
1mg
Catalogue number
CYT-982
Synonyms
Tumor Necrosis Factor Receptor Superfamily Member 13B, Tumor Necrosis Factor Receptor Superfamily, Member 13B, Transmembrane Activator And CAML Interactor ,TACI , Tumor Necrosis Factor Receptor 13B, CD267 Antigen, TNFRSF14B, CD267, CVID2, IGAD2, CVID, RYZN.
肿瘤坏死因子受体超家族成员 13B、肿瘤坏死因子受体超家族成员 13B、跨膜激活因子和 CAML 相互作用因子、TACI、肿瘤坏死因子受体 13B、CD267 抗原、TNFRSF14B、CD267、CVID2、IGAD2、CVID、RYZN。
Introduction
TNFRSF13B is a transmembrane receptor protein found predominantly on the surface of B cells . TACI was at first discovered owing to its ability to interact with calcium-modulator and cyclophilin ligand . Later on, it was found that TACI plays a key role in humoral immunity by interacting with two members of the TNF family. Also, TACI controls T cell-independent B cell antibody responses, isotype switching, and B cell homeostasis.
TNFRSF13B 是一种跨膜受体蛋白,主要存在于 B 细胞表面。 最初发现 TACI 是因为它能够与钙调节剂和亲环蛋白配体相互作用。 后来发现TACI通过与TNF家族的两个成员相互作用在体液免疫中起关键作用。 此外,TACI 控制不依赖 T 细胞的 B 细胞抗体反应、同种型转换和 B 细胞稳态。
Description
TACI produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 407 amino acids and having a molecular mass of 45.8kDa . TACI is expressed with a 242 amino acid hIgG-His tag at C-Terminus and purified by proprietary chromatographic techniques. |
Source
Sf9, Insect cells.
Physical Appearance
Sterile filtered colorless soltion.u
Formulation
TACI a protein solution contains Phosphate Buffered Saline , 30% glycerol and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
如果整个小瓶将在 2-4 周内使用,请在 4°C 下储存。
储存,在 -20°C 下冷冻更长时间。
对于长期储存,建议添加载体蛋白。
避免多次冻融循环。
储存,在 -20°C 下冷冻更长时间。
对于长期储存,建议添加载体蛋白。
避免多次冻融循环。
Purity
Greater than 90.0% as determined by -PAGE.
Amino acid sequence
ADLMSGLGRS RRGGRSRVDQ EERFPQGLWT GVAMRSCPEE QYWDPLLGTC MSCKTICNHQ SQRTCAAFCR SLSCRKEQGK FYDHLLRDCI SCASICGQHP KQCAYFCENK LRSPVNLPPE LRRQRSGEVE NNSDNSGRYQ GLEHRGSEAS PALPGLKLSA DQVALVYSLE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG KHHHHHH.
Usage
ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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