ProSpec-SCGB1A1 Human, His/CYT-752

Uteroglobin, Clara cell phospholipid-binding protein, CCPBP, Clara cells 10 kDa secretory protein, CC10, Secretoglobin family 1A member 1, Urinary protein 1, UP-1, UP1, Urine protein 1, SCGB1A1, CCSP, UGB, CC16.

Uteroglobin which belongs to the Secretoglobin superfamily, is a multifunctional protein that exerts anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. Uteroglobin is involved in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. SCGB1A1 is expressed by Clara cells, the non-ciliated, non-mucous secretory cells predominant in lung bronchioles, and by other epithelia which communicate with the external environment. On top of sequestering pro-inflammatory mediators and carcinogens, Uteroglobin is implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation. SCGB1A1 gene defects are associated with a susceptibility to asthma.

子宫珠蛋白属于分泌珠蛋白超家族，是一种多功能蛋白，通过结合磷脂和前列腺素等疏水小分子发挥抗炎和抗肿瘤作用。 子宫珠蛋白参与多种功能，包括抗炎、抑制磷脂酶 A2 和螯合疏水配体。 SCGB1A1 由 Clara 细胞（主要存在于肺细支气管中的非纤毛、非粘液分泌细胞）和与外部环境通信的其他上皮细胞表达。 除了隔离促炎介质和致癌物外，子宫珠蛋白还参与抑制细胞迁移和侵袭、血小板聚集和 T 细胞分化。 SCGB1A1 基因缺陷与哮喘易感性有关。

Uteroglobin Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 80 amino acids and including a 10 a.a N-terminal His tag. The total molecular mass is 9.2kDa .

在大肠杆菌中产生的 Uteroglobin Human Recombinant 是一种单一的、非糖基化的多肽链，含有 80 个氨基酸并包括一个 10 个氨基酸的 N 端 His 标签。 总分子量为9.2kDa。

Escherichia Coli.

Filtered White lyophilized powder.

Filtered and lyophilized from 0.5 mg/ml in 0.05M phosphate buffer and 0.075M NaCl, pH 7.4.

It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. SCGB1A1 is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

建议加入去离子水配制约 0.5mg/ml 的工作原液，让冻干颗粒完全溶解。 SCGB1A1 不是无菌的！ 在细胞培养中使用之前，请用适当的无菌过滤器过滤产品。

Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

将冻干蛋白储存在 -20°C。 重组后分装产品以避免重复的冷冻/解冻循环。 重组蛋白可在 4°C 下保存一段时间； 在 4°C 下两周后它没有显示任何变化。

Greater than 90.0% as determined by -PAGE.

MKHHHHHHASEICPSFQRVI ETLLMDTPSS YEAAMELFSP DQDMREAGAQ LKKLVDTLPQ KPRESIIKLM EKIAQSSLCN.

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