WNT7A Human
Wingless-Type MMTV Integration Site Family, Member 7A Human Recombinant
CYT-795
ProSpec-WNT7A Human/CYT-795 5µg
ProSpec-WNT7A Human/CYT-795 20µg
ProSpec-WNT7A Human/CYT-795 1mg
Catalogue number
CYT-795
Synonyms
Wingless-Type MMTV Integration Site Family, Member 7A, Proto-Oncogene Wnt7a Protein, Protein Wnt-7a.
Introduction
Wingless-Type MMTV Integration Site Family, Member 7A also known as WNT7A belongs to the WNT gene family, this family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT7A is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays an essential role in uterine smooth muscle pattering and maintenance of adult uterine function. In addition, Mutations in WNT7A have been associated with Fuhrmann and Al-Awadi Raas-Rothschild Schinzel phocomelia syndromes.
Wingless-Type MMTV 整合位点家族，成员 7A 也称为 WNT7A，属于 WNT 基因家族，该家族由编码分泌信号蛋白的结构相关基因组成。 这些蛋白质与肿瘤发生和几个发育过程有关，包括在胚胎发生过程中调节细胞命运和模式。 WNT7A 参与女性生殖道前后轴的发育，在子宫平滑肌模式和成人子宫功能的维持中也发挥着重要作用。 此外，WNT7A 的突变与 Fuhrmann 和 Al-Awadi Raas-Rothschild Schinzel phocomelia 综合征有关。
Description
WNT7A Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 341 amino acids and having a molecular mass of 38kDa.
WNT7A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
WNT7A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 WNT7A 人重组体是一条单一的、非糖基化的多肽链，包含 341 个氨基酸，分子量为 38kDa。
WNT7A 在 N 末端与 23 个氨基酸的 His-tag 融合，并通过专有色谱技术进行纯化。
WNT7A 在 N 末端与 23 个氨基酸的 His-tag 融合，并通过专有色谱技术进行纯化。
Source
Escherichia Coli.
Physical Appearance
Sterile filtered colorless solution.
Formulation
WNT7A protein solution containing 20mM Tris-HCl buffer , 10% glycerol and 0.4M Urea.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。 储存，在 -20°C 下冷冻更长时间。
对于长期储存，建议添加载体蛋白。
避免多次冻融循环。
对于长期储存，建议添加载体蛋白。
避免多次冻融循环。
Purity
Greater than 85.0% as determined by -PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSLGASIIC NKIPGLAPRQ RAICQSRPDA IIVIGEGSQM GLDECQFQFR NGRWNCSALG ERTVFGKELK VGSREAAFTY AIIAAGVAHA ITAACTQGNL SDCGCDKEKQ GQYHRDEGWK WGGCSADIRY GIGFAKVFVD AREIKQNART LMNLHNNEAG RKILEENMKL ECKCHGVSGS CTTKTCWTTL PQFRELGYVL KDKYNEAVHV EPVRASRNKR PTFLKIKKPL SYRKPMDTDL VYIEKSPNYC EEDPVTGSVG TQGRACNKTA PQASGCDLMC CGRGYNTHQY ARVWQCNCKF HWCCYVKCNT CSERTEMYTC K.
Usage
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ProSpec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。