ProSpec-CYTL1 Human/CYT-775

Cytokine-like protein 1, Protein C17, CYTL1, C4orf4, C17.

Cytokine-like protein 1 is a secreted protein. CYTL1 is expressed in CD34+ cell populations of bone marrow and cord blood which function as hematopoietic stem/progenitor cells. However, CYTL1 is not expressed in CD34- cells. Experiments with knock-out mice propose that CYTL1 is essential for the maintenance of cartilage homeostasis rather than cartilage and bone development, and loss of CYTL1 function is linked with experimental osteoarthritic cartilage destruction in mice.

细胞因子样蛋白 1 是一种分泌蛋白。 CYTL1 在作为造血干细胞/祖细胞的骨髓和脐带血的 CD34+ 细胞群中表达。 然而，CYTL1 不在 CD34- 细胞中表达。 对敲除小鼠的实验表明，CYTL1 对维持软骨稳态而不是软骨和骨骼发育至关重要，并且 CYTL1 功能的丧失与小鼠实验性骨关节炎软骨破坏有关。

CYTL1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 124 amino acids including a 10 a.a N-terminal His tag. The total molecular mass is 14.6kDa .

在大肠杆菌中产生的 CYTL1 Human Recombinant 是一个单一的、非糖基化的多肽链，包含 124 个氨基酸，包括一个 10 个氨基酸的 N 端 His 标签。 总分子量为14.6kDa。

Escherichia Coli.

Filtered White lyophilized powder.

CYTL1 was filtered and lyophilized from 0.5mg/ml in 20mM Tris buffer and 50mM NaCl, pH 7.5.

It is recommended to add deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. CYTL1 is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

将冻干蛋白储存在 -20°C。 重组后分装产品以避免重复的冷冻/解冻循环。 重组蛋白可在 4°C 下保存一段时间； 在 4°C 下两周后它没有显示任何变化。

Greater than 95.0% as determined by -PAGE.

MKHHHHHHASTPPTCYSRMR ALSQEITRDF NLLQVSEPSE PCVRYLPRLY LDIHNYCVLD KLRDFVASPP CWKVAQVDSL KDKARKLYTI MNSFCRRDLV FLLDDCNALE YPIPVTTVLP DRQR.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.