Vaspin Human
Vaspin Recombinant Human
CYT-1132
ProSpec-Vaspin Human/CYT-1132 5µg
ProSpec-Vaspin Human/CYT-1132 25µg
ProSpec-Vaspin Human/CYT-1132 1mg
Catalogue number
CYT-1132
Synonyms
Serpin A12 precursor, Visceral adipose-specific serpin, Visceral adipose tissue- derived serine protease inhibitor, Vaspin, OL-64, SERPINA12, Serine proteinase inhibitor, clade A, antitrypsin, alpha-1 antiproteinase.
Serpin A12 前体、内脏脂肪特异性 serpin、内脏脂肪组织来源的丝氨酸蛋白酶抑制剂、Vaspin、OL-64、SERPINA12、丝氨酸蛋白酶抑制剂、进化枝 A、抗胰蛋白酶、α-1 抗蛋白酶。
Introduction
Vaspin is a newly identified adipokine, which is a member of serine protease inhibitor family. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that induction of human vaspin mRNA expression in adipose tissue is regulated in a fat depot-specific manner and could be associated with parameters of obesity, insulin resistance, and glucose metabolism.
Vaspin 是一种新发现的脂肪因子,是丝氨酸蛋白酶抑制剂家族的成员。 Vaspin 也是一种独特的胰岛素增敏脂肪细胞因子。 最近的一份出版物表明,脂肪组织中人类 vaspin mRNA 表达的诱导以脂肪库特异性方式进行调节,并且可能与肥胖、胰岛素抵抗和葡萄糖代谢的参数有关。
Description
Vaspin Human Recombinant produced in E.Coli is a single, non- glycosylated polypeptide chain containing 394 amino acids and having a molecular mass of 45.1kDa.
Vaspin is purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 Vaspin Human Recombinant 是单条非糖基化多肽链,含有 394 个氨基酸,分子量为 45.1kDa。
Vaspin 通过专有的色谱技术进行纯化。
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered White lyophilized powder.
Formulation
Lyophilized from a 0.2μm filtered concentrated solution in 20mM Tris-HCl, pH 8.0, 150mM NaCl and 0.02 % Tween-20.
从 20mM Tris-HCl、pH 8.0、150mM NaCl 和 0.02% Tween-20 中的 0.2μm 过滤浓缩溶液冻干。
Solubility
It is recommended to reconstitute the lyophilized Vaspin in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
建议在不低于 100µg/ml 的无菌 18MΩ-cm H2O 中复溶冻干的 Vaspin,然后可以进一步稀释成其他水溶液。
Stability
Lyophilized Vaspin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Vaspin should be stored at 4°C between 2-7 days and for future use below -18°C.
Please prevent freeze-thaw cycles.
冻干的 Vaspin 虽然在室温下可稳定保存 3 周,但应在 -18°C 以下干燥储存。 复溶后,Vaspin 应在 4°C 下储存 2-7 天,以备将来在 -18°C 以下使用。
请防止冻融循环。
Purity
Greater than 98.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.
Amino acid sequence
LKPSFSPRNY KALSEVQGWK QRMAAKELAR QNMDLGFKLL KKLAFYNPGR NIFLSPLSIS TAFSMLCLGA QDSTLDEIKQ GFNFRKMPEK DLHEGFHYII HELTQKTQDL KLSIGNTLFI DQRLQPQRKF LEDAKNFYSA ETILTNFQNL EMAQKQINDF ISQKTHGKIN NLIENIDPGT VMLLANYIFF RARWKHEFDP NVTKEEDFFL EKNSSVKVPM MFRSGIYQVG YDDKLSCTIL EIPYQKNITA IFILPDEGKL KHLEKGLQVD TFSRWKTLLS RRVVDVSVPR LHMTGTFDLK KTLSYIGVSK IFEEHGDLTK IAPHRSLKVG EAVHKAELKM DERGTEGAAG TGAQTLPMET PLVVKIDKPY LLLIYSEKIP SVLFLGKIVN PIGK.
Usage
Related Products
-
Vaspin Human, His